Improved prep‐scale isolation of glucosinolates from cruciferous vegetables using a novel stationary phase

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Glucosinolates from Cruciferous Vegetables for Cancer Chemoprevention

Prevention and/or protection against chemical carcinogens by phytochemicals present in extensively consumed glucosinolate-containing cruciferous vegetables is of great of interest, as they provide a safe and cost effective means of combating cancer. Extensive epidemiological studies revealed repeatedly an inverse relationship between cruciferous vegetable consumption and the incidence of cancer...

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Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables.

Isothiocyanates and their naturally occurring glucosinolate precursors are widely consumed as part of a diet rich in cruciferous vegetables. When plant cells are damaged, glucosinolates are released and converted to isothiocyanates by the enzyme myrosinase. Many isothiocyanates inhibit the neoplastic effects of various carcinogens at a number of organ sites. Consequently, these agents are attra...

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Cancer is a leading cause of death in North America, and poor diet is suspected as a causative factor in 1/3 of all cancer deaths. Epidemiologic studies have shown that a diet rich in cruciferous vegetables such as broccoli is protective against many cancers. Broccoli contains sulforaphane (SI), a substance that activates promoter elements in certain phase II detoxification enzymes of animals, ...

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In vitro antiproliferative activity of isothiocyanates and nitriles generated by myrosinase-mediated hydrolysis of glucosinolates from seeds of cruciferous vegetables.

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2010

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fasebj.24.1_supplement.540.18